Metabolic Engineering

By ResearcherStore Categories: C-Science
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About Course

Metabolic engineering is an emerging field of biotechnology/bioprocess engineering which aims towards the purposeful modification of cellular (metabolic, gene regulatory, and signaling) processes/networks to achieve desirable goals such as enhanced production of metabolites including pharmaceuticals, biofuels and biochemicals, and other biotechnology products.

This course aims to provide fundamental and advanced knowledge in the development of microbial strain for bioproduction through metabolic engineers.

What Will You Learn?

  • Learn the basics of Metabolic Engineering from A to Z

Course Content

Metabolic Engineering

  • 01 Virtual Welcome
    00:00
  • 02 Group Projects
    00:00
  • 03 Intro to MFA
    00:00
  • 04 Metabolic Databases
    00:00
  • 05 Intro to FBA
    00:00
  • 06 FBA Part 2
    00:00
  • 07 FBA Part 3
    00:00
  • 08 GEM Database
    00:00
  • 09 GEM Files
    00:00
  • 10 OptKnock
    00:00
  • 11 Intro to 13C MFA
    00:00
  • 12 13C MFA Part 2
    00:00
  • 13 13C MFA Part 3
    00:00
  • 14 Regulatory Modalities
    00:00
  • 15 Positive & Negative
    00:00
  • 16 Negative Feedback
    00:00
  • 17 Trp Operon
    00:00
  • 18 Feedback Resistant Enzymes
    00:00
  • 19 RNA Polymerase Anatomy
    00:00
  • 20 Promoters
    00:00
  • 21 The Ribosome Binding Site
    00:00
  • 22 The RBS Calculator
    00:00
  • 23 Tradeoffs of translation
    00:00
  • 24 Inducible promoters
    00:00
  • 25 Building biosensors
    00:00
  • 26 Biosensor details
    00:00
  • 27 TF Cooperativity
    00:00
  • 28 Dynamic knockdown
    00:00
  • 29 Industrial DMC
    00:00
  • 30 Synthetic circuits
    00:00
  • 31 Genome editing
    00:00
  • 32 Nucleases
    00:00
  • 33 CRISPR Metabolic Engr
    00:00
  • 34 Recombineering
    00:00
  • 35 MAGE
    00:00
  • 36 MAGE Applied
    00:00
  • 37 Genomes for new chemistry
    00:00
  • 38 Genomes & aldehydes
    00:00
  • 39 Aldehyde reductases
    00:00
  • 40 Creating a RARE genome
    00:00
  • 41 Recoded E. coli
    00:00
  • 42 Other recoded genomes
    00:00
  • 43 Expanded genetic alphabet
    00:00
  • 44 Minimal genomes
    00:00
  • 45 Refactored genomes
    00:00
  • 46 De novo pathways
    00:00
  • 47 Experimental design steps
    00:00
  • 48 Retrobiosynthesis
    00:00
  • 49 Unnatural targets
    00:00

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