In this work, an advanced novel small-scale NOMA utilizing physical layer security (PLS) techniques, used for enhancing communication security and reliability for two users is proposed. This work is motivated by the recent exclusion of the conventional power-domain non-orthogonal multiple access (NOMA) from 3GPP Release 17. This was due to its performance degradation, in terms of successive interference cancellation (SIC) and channel estimation errors. The proposed model eliminates user interference and uses the wireless channel characteristics to completely degrade the received signal at the eavesdropper’s terminal. More specifically, auxiliary signals are precisely designed and superimposed on top of user signals from a dual-transmitter system to provide perfect secrecy against external and internal eavesdroppers, while providing low complexity at the receiver and eliminating user interference. Moreover, antenna selection-based techniques and artificial channel manipulator filters are employed to further enhance the security of the system. The efficiency and novelty of the proposed system are presented via mathematical analysis and validated by Monte Carlo simulations. Results obtained indicate that the proposed model achieves secure and efficient communication, suitable for low power consumption, limited processing, and delay-sensitive applications.